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eMediNexus 01 January 2022
A study was conducted by Savarino and colleagues to determine the effects of single daily doses of placebo, nizatidine 300 mg, ranitidine 300 mg and famotidine 40 mg, administered at 22:00 h. The effects of the study drugs were compared in 16 patients with healed duodenal ulcers. All the study participants were subjected to the said treatment on four different occasions.
The acid suppression with nizatidine appears to be shorter-lasting compared to that with ranitidine and famotidine.
Source: Savarino V, Mela GS, Zentilin P, et al. Comparison of the effects of placebo, ranitidine, famotidine and nizatidine on intragastric acidity by means of continuous pH recording. Digestion. 1989;42(1):1-6.
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